肝动脉化疗栓塞TACE用于肝细胞癌的

Purpose:Toreportcurrentpracticesoftransarterialchemoembolization(TACE)byinterventionalradiologists(IR)forhepatocellularcarcinoma(HCC)throughaFrenchnationalsurvey.

目的:为了报告肝动脉化疗栓塞用于肝细胞癌(HCC)治疗的现况,进行了一次针对法国全国介入放疗科医生的调查。

Materialsandmethods:Anelectronicsurveywassentbye-mailtoIRsperformingTACEin32privateorpubliccenters.Thesurveyincluded66itemsincludingindicationsforTACE,technicalaspectsofTACE,otherlocallyavailabletreatmentsforHCC,follow-upimagingandgeneralaspectsofinterventionalradiologypractices.

材料和方法:通过电子邮件调查了名来自法国32医院的、从事肝动脉化疗栓塞(TACE)的介入放射科医生。调查问卷设置了66个条目,包括TACE的适应症、TACE的技术、肝细胞癌的其它局部治疗方法,影像学随访和介入放射学实践的常识问题。

Results:Atotalof64IRs(64/;27%)answeredthesurvey.EachIRperformedameanof49±45(SD)TACEproceduresperyear.MarkedvariationsinindicationsforTACEinHCCwereobserved.SixpercentofIRs(4/64)treatedonlypatientswithBarcelonaClinicLiverCancer(BCLC)stageBHCC.Antibioprophylaxiswasnotusedby43/64ofIRs(67%).ThenumberofHCCnoduleswasconsideredtoselectconventionalTACEversusdrug-elutingbeadsTACE(DEB-TACE)by17/49IRs(35%)followedbypatientperformancestatusandChild-Pughscoreby6/49IRs(12%).Seventy-threepercentofIRs(45/62)treatednodulesselectivelyinpatientswithunilobardiseasewithcTACE.Thirty-threepercentofIRs(21/64)plannedsystematicallyasecondTACEsession.Doxorubicinwasthemostfrequentlyuseddrug(52/64;81%)and15/64IRs(23%)usedgelatinespongeastheonlyembolicagent.ForDEB-TACE,-μmbeadswereusedby26/49IRs(53%)andnoadditionalembolizationwasperformedby19/48IRs(39%).Monopolarradiofrequencytechniquewaswidelyavailable(59/63;94%)


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